Recombinant Human HAO1 Protein, N-His-tagged, Biotinylated

• Cat.No.: HAO1-3612HB
• Product Overview: Recombinant human HAO1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. Purified protein was labeled with Biotin in vitro.

Specification

• Description: This gene is one of three related genes that have 2-hydroxyacid oxidase activity yet differ in encoded protein amino acid sequence, tissue expression and substrate preference. Subcellular location of the encoded protein is the peroxisome. Specifically, this gene is expressed primarily in liver and pancreas and the encoded protein is most active on glycolate, a two-carbon substrate. The protein is also active on 2-hydroxy fatty acids. The transcript detected at high levels in pancreas may represent an alternatively spliced form or the use of a multiple near-consensus upstream polyadenylation site.
• Source: E. coli
• Species: Human
• Tag: His
• Form: Liquid. 1×PBS buffer.
• Molecular Mass: 45.0 kDa(406aa), confirmed by MALDI-TOF
• AA Sequence: MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSMLPR LICINDYEQH AKSVLPKSIY DYYRSGANDE ETLADNIAAF SRWKLYPRMLRNVAETDLST SVLGQRVSMP ICVGATAMQR MAHVDGELAT VRACQSLGTG MMLSSWATSS IEEVAEAGPE ALRWLQLYIY KDREVTKKLVRQAEKMGYKA IFVTVDTPYL GNRLDDVRNR FKLPPQLRMK NFETSTLSFS PEENFGDDSG LAAYVAKAID PSISWEDIKW LRRLTSLPIVAKGILRGDDA REAVKHGLNG ILVSNHGARQ LDGVPATIDV LPEIVEAVEG KVEVFLDGGV RKGTDVLKAL ALGAKAVFVG RPIVWGLAFQGEKGVQDVLE ILKEEFRLAM ALSGCQNVKV IDKTLVRKNP LAVSKI
• Purity: >95% by SDS - PAGE
• Storage: Aliquot and store at -20 centigrade or -70 centigrade.Avoid repeated freezing and thawing cycles.
• Concentration: 1.0 mg/ml

Gene Information

• Gene Name: HAO1 hydroxyacid oxidase 1 [ Homo sapiens (human) ]
• Official Symbol: HAO1
• Synonyms: GO; GOX; GOX1; HAOX1
• Gene ID: 54363
• mRNA Refseq: NM_017545.3
• Protein Refseq: NP_060015.1
• MIM: 605023
• UniProt ID: Q9UJM8