Recombinant Human HACL1, T7-tagged

• Cat.No.: HACL1-2960H
• Product Overview: Recombinant Human HACL1 (1-578 aa) is expressed inE.Coliwith a T7 tag at N-terminus.

Specification

• Species: Human
• Source: E.coli
• Tag: T7
• Protein Length: 1-578 a.a.
• Description: By analyzing 1,780,295 5"-end sequences of human full-length cDNAs derived from 164 kinds of oligo-cap cDNA libraries, we identified 269,774 independent positions of transcriptional start sites (TSSs) for 14,628 human RefSeq genes. These TSSs were clustered into 30,964 clusters that were separated from each other by more than 500 bp and thus are very likely to constitute mutually distinct alternative promoters. To our surprise, at least 7674 (52%) human RefSeq genes were subject to regulation by putative alternative promoters (PAPs). On average, there were 3.1 PAPs per gene, with the composition of one CpG-island-containing promoter per 2.6 CpG-less promoters.
• MW: 12499 Da.
• Purity: 95%.
• Formulation: 10 mM Tris. pH 8.0. 0.1% Triton X-100.0.002% NaN3.
• Application: MS. SDS.

Gene Information

• Gene Name: HACL1 2-hydroxyacyl-CoA lyase 1 [ Homo sapiens ]
• Synonyms: HACL1; 2-hydroxyacyl-CoA lyase 1;HSPC279; 2-HPCL; FLJ55041, HPCL; HPCL2, PHYH2; 1600020H07Rik; 2-hydroxyphytanol-CoA lyase; 2-hydroxyphytanoyl-CoA lyase; phytanoyl-CoA 2-hydroxylase 2; phytanoyl-CoA hydroxylase 2; EC 4.1.-.-
• Gene ID: 26061
• mRNA Refseq: NM_012260
• Protein Refseq: NP_036392
• MIM: 604300
• UniProt ID: Q9UJ83
• Chromosome Location: 3p25.1
• Pathway: Peroxisome; Metabolism of lipids and lipoproteins
• Function: carbon-carbon lyase activity; identical protein binding; magnesium ion binding; thiamin pyrophosphate binding