HACL1
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Official Full Name
2-hydroxyacyl-CoA lyase 1 -
Synonyms
HACL1;2-hydroxyacyl-CoA lyase 1;2 hydroxyphytanoyl CoA lyase , HPCL;2 HPCL;PHYH2;2 hydroxyphytanoyl CoA lyase;1600020H07Rik;2 hydroxyacyl CoA lyase 1;FLJ55041;HPCL;HPCL2;HSPC279;Phytanoyl CoA 2 hydroxylase 2;Phytanoyl CoA hydroxylase 2;2-hydroxyphytanol-CoA lyase;phytanoyl-CoA hydroxylase 2;2-hydroxyphytanoyl-CoA lyase;phytanoyl-CoA 2-hydroxylase 2;2-HPCL
Recombinant Proteins
- Human
- Zebrafish
- Rat
- Chicken
- Mouse
- E.coli
- Mammalian Cells
- Wheat Germ
- HEK293
- Human Cells
- In Vitro Cell Free System
- His
- T7
- GST
- Non
- Avi
- Fc
- Flag
- DDK
- Myc
Involved Pathway
HACL1 involved in several pathways and played different roles in them. We selected most pathways HACL1 participated on our site, such as Peroxisome, which may be useful for your reference. Also, other proteins which involved in the same pathway with HACL1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Peroxisome | MVK,BAAT,SLC27A2,ABCD4,ACSL4A,PEX10,SOD1,PEX2,ACSL4B,PXMP2 |
Protein Function
HACL1 has several biochemical functions, for example, carbon-carbon lyase activity,cofactor binding,identical protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by HACL1 itself. We selected most functions HACL1 had, and list some proteins which have the same functions with HACL1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| cofactor binding | ACLY,DDO,UROS,WWOX,TYMS,C3,TKT,ASNS,PHYH,DAO |
| identical protein binding | C1QTNF9,RABAC1,DYNLT1A,GOT2A,TPRG1L,DES,NIF3L1,L1CAM,ETNPPL,BAX |
| magnesium ion binding | ERN2,ALPI,CIB2,MAP3K5,RPS6KA3B,IDH3G,ICK,ILVBL,ATP4A,IDH3B |
| thiamine pyrophosphate binding | ILVBL,DHTKD1,OGDH,OGDHA |
| receptor binding | PRDX5,TYROBP,FGF6A,H2-Q10,MLYCD,YES1,FYB,ADCYAP1,ENSA,FGF18B |
| protein binding | ING5,MAGEB6,ZBTB1,ZNF488,EIF4A1,MCL1,BUC,KLRK1,FBN1,EFTUD2 |
Interacting Protein
HACL1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HACL1 here. Most of them are supplied by our site. Hope this information will be useful for your research of HACL1.
ZMYND19;MAGEB6;MAPK6;PEX5
Resources
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References
- Lonsdale, D; et al. Thiamine and magnesium deficiencies: Keys to disease. MEDICAL HYPOTHESES 84:129-134(2015).
- Mezzar, S; de Schryver, E; et al. RP-HPLC-fluorescence analysis of aliphatic aldehydes: application to aldehyde-generating enzymes HACL1 and SGPL1. JOURNAL OF LIPID RESEARCH 55:573-582(2014).
