Recombinant Human H2AFX protein

Cat.No. : H2AFX-124H
Product Overview : Recombinant human full-length, non-fusion H2AX protein was expressed in E. coli.
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Species : Human
Source : E.coli
Tag : Non
Form : 1.0 mg/ml, sterile-filtered, in 20 mM pH 8.0 Tris-HCl Buffer, with proprietary formulation of NaCl, KCl, EDTA, arginine, DTT and Glycerol.
AA Sequence : MSGRGKTGGKARAKAKSRSSRAGLQFPVGRVHRLLRKGHYAERVGAGAPVYLAAVLEYLTAEILELAGNAARDNK KTRIIPRHLQLAIRNDEELNKLLGGVTIAQGGVLPNIQAVLLPKKTSATVGPKAPSGGKKATQASQEY
Purity : >90% by SDS-PAGE
Applications : 1. Soluble protein which may be used as substrate for enzymatic assay.2. Active protein, for in vitro histone /DNA reconstitution assay.3. As Immunogen for specific antibody production.
Storage : Keep at -20°C for long term storage. Product is stable at 4 °C for at least 7 days.
Gene Name H2AFX H2A histone family, member X [ Homo sapiens ]
Official Symbol H2AFX
Synonyms H2AFX; H2A histone family, member X; H2AX; histone H2A.x; H2AX histone; H2A.X; H2A/X;
Gene ID 3014
mRNA Refseq NM_002105
Protein Refseq NP_002096
MIM 601772
UniProt ID P16104
Chromosome Location 11q23.3
Pathway ATM mediated phosphorylation of repair proteins, organism-specific biosystem; ATM mediated response to DNA double-strand break, organism-specific biosystem; Amyloids, organism-specific biosystem; Assembly of the RAD50-MRE11-NBS1 complex at DNA double-strand breaks, organism-specific biosystem; Cell Cycle, organism-specific biosystem; Chromosome Maintenance, organism-specific biosystem; DNA Repair, organism-specific biosystem;
Function DNA binding; enzyme binding; histone binding; protein binding;

Not For Human Consumption!

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