Recombinant Human GYPC, GST-tagged

• Cat.No.: GYPC-13632H
• Product Overview: Recombinant Human GYPC protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Description: Glycophorin C (GYPC) is an integral membrane glycoprotein. It is a minor species carried by human erythrocytes, but plays an important role in regulating the mechanical stability of red cells. A number of glycophorin C mutations have been described. The Gerbich and Yus phenotypes are due to deletion of exon 3 and 2, respectively. The Webb and Duch antigens, also known as glycophorin D, result from single point mutations of the glycophorin C gene. The glycophorin C protein has very little homology with glycophorins A and B. Alternate splicing results in multiple transcript variants.
• Source: E.coli
• Species: Human
• Tag: GST
• Protein length: 1-128a.a.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: GYPC glycophorin C (Gerbich blood group) [ Homo sapiens ]
• Official Symbol: GYPC
• Synonyms: GYPC; glycophorin C (Gerbich blood group); glycophorin-C; CD236; CD236R; Ge; GPC; GYPD; glycophorin-D; glycoconnectin; glycoprotein beta; sialoglycoprotein D; GE; GPD; PAS-2; MGC117309; MGC126191; MGC126192
• Gene ID: 2995
• mRNA Refseq: NM_001256584
• Protein Refseq: NP_001243513
• UniProt ID: P04921
• Chromosome Location: 2q14-q21
• Pathway: Malaria, organism-specific biosystem; Malaria, conserved biosystem
• Function: protein binding