GYPC
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Official Full Name
glycophorin C (Gerbich blood group) -
Overview
Glycophorin C (GYPC) is an integral membrane glycoprotein. It is a minor species carried by human erythrocytes, but plays an important role in regulating the mechanical stability of red cells. A number of glycophorin C mutations have been described. The Gerbich and Yus phenotypes are due todeletion of exon 3 and 2, respectively. The Webb and Duch antigens, also known as glycophorin D, result from single point mutations of the glycophorin C gene. The glycophorin C protein has very little homology with glycophorins A and B. -
Synonyms
GYPC;glycophorin C (Gerbich blood group);glycophorin-C;CD236;CD236R;Ge;GPC;GYPD;GLPC;GLPC_HUMAN;Glycoconnectin;Glycophorin D;Glycophorin-D;Glycoprotein beta;GPD;MGC117309;MGC126191;MGC126192;PAS 2;PAS-2;Sialoglycoprotein D;OTTHUMP00000162176;OTTHUMP00000203779
Recombinant Proteins
- Human
- Chicken
- Zebrafish
- Mouse
- Rat
- E.coli
- Mammalian Cell
- Wheat Germ
- HEK293
- HEK293T
- In Vitro Cell Free System
- Mammalian cells
- E.coli expression system
- GST
- His
- His&GST
- Non
- Myc&DDK
- His&Fc&Avi
Involved Pathway
GYPC involved in several pathways and played different roles in them. We selected most pathways GYPC participated on our site, such as Malaria, which may be useful for your reference. Also, other proteins which involved in the same pathway with GYPC were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Malaria | KLRC4-KLRK1,KLRB1,MYD88,ITGB2L,MET,HGF,COMP,HBA1,TNF,IL12A |
Protein Function
GYPC has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GYPC itself. We selected most functions GYPC had, and list some proteins which have the same functions with GYPC. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | GIMAP7,F7,GABARAPL1,SEMA6A,ZFAND2B,USP37,TET2,C8orf33,SRSF10,WEE1 |
Interacting Protein
GYPC has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GYPC here. Most of them are supplied by our site. Hope this information will be useful for your research of GYPC.
MPP1;EPB41
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References
- Uchikawa, M; Tsuneyama, H; et al. A new high-molecular-weight glycophorin C variant with a duplication of exon 2 in the glycophorin C gene. TRANSFUSION MEDICINE 7:305-309(1997).
- Guzvic, M; Braun, B; et al. Combined Genome and Transcriptome Analysis of Single Disseminated Cancer Cells from Bone Marrow of Prostate Cancer Patients Reveals Unexpected Transcriptomes. CANCER RESEARCH 74:7383-7394(2014).
