Recombinant Human GSR Protein (Met44-Arg522), N-His tagged

• Cat.No.: GSR-2514H
• Product Overview: Recombinant human GSR (Met44-Arg522) protein fused with the N-His tag was expressed in E. coli.

Specification

• Description: This gene encodes a member of the class-I pyridine nucleotide-disulfide oxidoreductase family. This enzyme is a homodimeric flavoprotein. It is a central enzyme of cellular antioxidant defense, and reduces oxidized glutathione disulfide (GSSG) to the sulfhydryl form GSH, which is an important cellular antioxidant. Rare mutations in this gene result in hereditary glutathione reductase deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been found.
• Source: E. coli
• Species: Human
• Tag: His
• Molecular Mass: 54.01 kDa
• Protein length: Met44-Arg522
• Purity: >90 % as determined by SDS-PAGE.
• Notes: For research use only.
• Storage: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 centigrade for one week. Store at -20 to -80 centigrade for twelve months from the date of receipt.
• Storage Buffer: 0.01M PBS, pH 7.4, 0.02 % NLS
• Reconstitution: Reconstitute in sterile water for a stock solution.
• Shipping: In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.

Gene Information

• Gene Name: GSR glutathione reductase [ Homo sapiens (human) ]
• Official Symbol: GSR
• Synonyms: GSR; glutathione reductase; glutathione reductase, mitochondrial; GR; GRase; MGC78522
• Gene ID: 2936
• mRNA Refseq: NM_000637
• Protein Refseq: NP_000628
• MIM: 138300
• UniProt ID: P00390