Recombinant Human GSK3B (1-351aa), His-tagged

• Cat.No.: GSK3B-2858H
• Product Overview: Theprotein was expressed as 6*his-tagged fusion protein by E. coliand purified by Ni-sepharose

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Description: Glycogensynthase kinase 3 beta, also known as GSK3B, is an enzyme that in humans isencoded by the GSK3B gene
• Sequence: 1-351aa
• Storage buffer: 1MPBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazoleand 0.7% Sarcosyl, 15%glycerol.
• Storage: Theprotein is stored in PBS buffer at - 20°C. Repeated freeze-thaw cycles shouldbe avoided.

Gene Information

• Gene Name: GSK3B glycogensynthase kinase 3 beta [ Homo sapiens ]
• Official Symbol: GSK3B
• Synonyms: GSK3B; glycogen synthase kinase3 beta; Glycogen synthase kinase-3 beta; GSK-3 beta; EC 2.7.11.26; glycogensynthase kinase -3 beta; GSK3beta isoform
• Gene ID: 2932
• mRNA Refseq: NM_001146156
• Protein Refseq: NP_001139628
• MIM: 605004
• UniProt ID: P49841
• Chromosome Location: 3q13.3
• Pathway: Chemokine signaling pathway; Alzheimer"sdisease; Axon guidance; B cell receptor signaling pathway; Basal cellcarcinoma; Cell cycle; Colorectal cancer; Endometrial cancer; ErbB signalingpathway; Focal adhesion; Hedgehog signaling pathway; Insulin signalingpathway; Melanogenesis; Neurotrophin signaling pathway; Prostate cancer; Tcell receptor signaling pathway; Wnt signaling pathway; Axon guidance;Signaling by Wnt; Signalling by NGF
• Function: ATP binding; nucleotidebinding; transferase activity; glycogen synthase kinase 3 activity; proteinkinase A catalytic subunit binding; tau-protein kinase activity; NF-kappaBbinding; beta-catenin binding; p53 binding