Recombinant Human GRID2, His-tagged

• Cat.No.: GRID2-13530H
• Product Overview: Recombinant Human GRID2 protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 20-358a.a.
• Description: The protein encoded by this gene is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential. Two transcript variants encoding different isoforms have been found for this gene.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.

Gene Information

• Gene Name: GRID2 glutamate receptor, ionotropic, delta 2 [ Homo sapiens ]
• Official Symbol: GRID2
• Synonyms: GRID2; glutamate receptor, ionotropic, delta 2; glutamate receptor delta-2 subunit; GluD2; GluR delta 2; GluR-delta-2; gluR delta-2 subunit; MGC117022; MGC117023; MGC117024
• Gene ID: 2895
• mRNA Refseq: NM_001510
• Protein Refseq: NP_001501
• MIM: 602368
• UniProt ID: O43424
• Chromosome Location: 4q22
• Pathway: Long-term depression, organism-specific biosystem; Long-term depression, conserved biosystem; Neuroactive ligand-receptor interaction, organism-specific biosystem; Neuroactive ligand-receptor interaction, conserved biosystem
• Function: extracellular-glutamate-gated ion channel activity; glutamate receptor activity; ion channel activity; ionotropic glutamate receptor activity; receptor activity; transporter activity