Recombinant Human GRIA3 protein, His & T7-tagged

• Cat.No.: GRIA3-1352H
• Product Overview: Recombinant Human GRIA3 aa. (Thr649~Asn823 (Accession# P42263) fused with N-terminal His & T7 tag was produced in E. coli cells.

Specification

• Species: Human
• Source: E.coli
• Tag: His&T7
• Protein Length: Thr649~Asn823
• Description: Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits, arranged to form ligand-gated ion channels. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. The subunit encoded by this gene belongs to a family of AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate)-sensitive glutamate receptors, and is subject to RNA editing (AGA->GGA; R->G). Alternative splicing at this locus results in different isoforms, which may vary in their signal transduction properties.
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 22.9kDa
• Endotoxin: <1.0EU per 1µg (determined by the LAL method)
• Purity: >95%
• Characteristic: The isoelectric point is 9.2.
• Applications: SDS-PAGE; WB; ELISA; IP.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Storage buffer: Supplied as lyophilized form in 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% sarcosyl, 5% trehalose, and preservative
• Reconstitution: Reconstitute in sterile ddH2O.

Gene Information

• Gene Name: GRIA3 glutamate ionotropic receptor AMPA type subunit 3 [ Homo sapiens (human) ]
• Official Symbol: GRIA3
• Synonyms: GRIA3; glutamate ionotropic receptor AMPA type subunit 3; GLUR3; GLURC; GluA3; MRX94; GLUR-C; GLUR-K3; glutamate receptor 3; AMPA-selective glutamate receptor 3; dJ1171F9.1; gluR-3; glutamate receptor C; glutamate receptor subunit 3; glutamate receptor, ionotrophic, AMPA 3; glutamate receptor, ionotropic, AMPA 3
• Gene ID: 2892
• mRNA Refseq: NM_000828.4
• Protein Refseq: NP_000819.3
• UniProt ID: P42263