Recombinant Human GIMAP6, His-tagged

• Cat.No.: GIMAP6-15889H
• Product Overview: Recombinant human GIMAP6 protein, fused to His tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Specification

• Description: GIMAP6 is a member of the GTPases of immunity-associated proteins (GIMAP) family. GIMAP proteins contain GTP-binding and coiled-coil motifs, and may play roles in the regulation of cell survival. Decreased expression of this gene may play a role in non-small cell lung cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, which is found in a cluster with seven additional GIMAP genes on the long arm of chromosome 7.
• Source: E. coli
• Species: Human
• Tag: His
• Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 30% glycerol, 1mM DTT.
• Molecular Mass: 35 kDa (315aa), confirmed by MALDI-TOF(Molecular size on SDS-PAGE will appear higher)
• Protein length: 1-292aa
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSMEEEEYE QIPQENPPEE LSQDPVLELS GGLREKEQKT PRRLRLILMG KTGSGKSATG NSILGRDVFE SKLSTRPVTK TSQRRSREWA GKELEVIDTP NILSPQVSPE VADAICQAIV LSAPGPHAVL LVTQLGRFTD EDQQVVRRLQ EVFGVGVLGH TILVFTRKED LAGGSLEDYV RETNNQALAW LDVTLARRHC GFNNRAQGEE QEAQLRELME KVEAIMWENE GDYYSNKAYQ YTQQNFRLKE LQERQVSQGQ GSEDVPGEES WLEGLSQIQK ESEEAHRCLL GKADL
• Purity: >85% by SDS - PAGE
• Applications: SDS-PAGE
• Storage: Can be stored at 4°C short term. For long term storage, aliquot and store at at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
• Concentration: 0.5 mg/ml (determined by Bradford assay)

Gene Information

• Gene Name: GIMAP6 GTPase, IMAP family member 6 [ Homo sapiens ]
• Official Symbol: GIMAP6
• Synonyms: GIMAP6; GTPase, IMAP family member 6; GTPase IMAP family member 6; FLJ22690; immune associated nucleotide 2; immune associated nucleotide 6; IAN2; IAN6; IAN-2; IAN-6; DKFZp686A01175
• Gene ID: 474344
• mRNA Refseq: NM_024711
• Protein Refseq: NP_078987
• UniProt ID: Q6P9H5
• Chromosome Location: 7q36.1
• Function: GTP binding; nucleotide binding