Recombinant Human GIMAP2, GST-tagged

• Cat.No.: GIMAP2-13255H
• Product Overview: Recombinant Human GIMAP2 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Description: Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. Alternative splicing of this gene results in three tissue-specific forms of glucokinase, one found in pancreatic islet beta cells and two found in liver. The protein localizes to the outer membrane of mitochondria. In contrast to other forms of hexokinase, this enzyme is not inhibited by its product glucose-6-phosphate but remains active while glucose is abundant. Mutations in this gene have been associated with non-insulin dependent diabetes mellitus (NIDDM), maturity onset diabetes of the young, type 2 (MODY2) and persistent hyperinsulinemic hypoglycemia of infancy (PHHI).
• Source: E.coli
• Species: Human
• Tag: GST
• Protein length: 1-258a.a.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: GIMAP2 GTPase, IMAP family member 2 [ Homo sapiens ]
• Official Symbol: GIMAP2
• Synonyms: GIMAP2; GTPase, IMAP family member 2; GTPase IMAP family member 2; DKFZp586D0824; HIMAP2; IMAP2; immunity associated protein 2; immunity-associated protein 2; MGC24275
• Gene ID: 26157
• mRNA Refseq: NM_015660
• Protein Refseq: NP_056475
• MIM: 608085
• UniProt ID: Q9UG22
• Chromosome Location: 7q36.1
• Function: GTP binding; nucleotide binding