Recombinant Human GFUS Protein, His-tagged

• Cat.No.: GFUS-026H
• Product Overview: Recombinant N-terminal histidine-tagged human GDP-L-fucose synthase (2-321) was purified from E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• ProteinLength: 2-321
• Description: Tissue specific transplantation antigen P35B is a NADP(H)-binding protein. It catalyze the two-step epimerase and the reductase reactions in GDP-D-mannose metabolism, converting GDP-4-keto-6-D-deoxymannose to GDP-L-fucose. GDP-L-fucose is the substrate of several fucosyltransferases involved in the expression of many glycoconjugates, including blood group ABH antigens and developmental adhesion antigens. Mutations in this gene may cause leukocyte adhesion deficiency, type II.
• Molecular Mass: 37.98 kDa
• Purity: ≥90% as determined by SDS-PAGE
• Stability: ≥ 6 months
• Storage: At -80 centigrade.
• Storage Buffer: 50 mM HEPES, pH 8.0, with 150 mM sodium chloride and 10% glycerol

Gene Information

• Gene Name: GFUS GDP-L-fucose synthase [ Homo sapiens (human) ]
• Official Symbol: GFUS
• Synonyms: GFUS; GDP-L-fucose synthase; FX; P35B; TSTA3; SDR4E1; GDP-L-fucose synthase; 3-5 epimerase/4-reductase; GDP-4-keto-6-deoxy-D-mannose epimerase-reductase; GDP-4-keto-6-deoxy-D-mannose-3,5-epimerase-4-reductase; red cell NADP(H)-binding protein; short chain dehydrogenase/reductase family 4E, member 1; testis tissue sperm-binding protein Li 45a; tissue specific transplantation antigen 3; tissue specific transplantation antigen P35B; EC 1.1.1.271
• Gene ID: 7264
• mRNA Refseq: NM_003313
• Protein Refseq: NP_003304
• MIM: 137020
• UniProt ID: Q13630