Description :	This gene encodes one of the major intermediate filament proteins of mature astrocytes. It is used as a marker to distinguish astrocytes from other glial cells during development. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Protein length :	432 amino acids
Molecular Weight :	73.590kDa inclusive of tags
Source :	Wheat germ
Tissue specificity :	Expressed in cells lacking fibronectin.
Form :	Liquid
Purity :	Proprietary Purification
Storage buffer :	pH: 8.00Constituents:0.3% Glutathione, 0.79% Tris HCl
Storage :	Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
Sequences of amino acids :	MERRRITSAARRSYVSSGEMMVGGLAPGRRLGPGTRLSLA RMPPPLPTRVDFSLAGALNAGFKETRASERAEMMELNDRF ASYIEKVRFLEQQNKALAAELNQLRAKEPTKLADVYQAEL RELRLRLDQLTANSARLEVERDNLAQDLATVRQKLQDETN LRLEAENNLAAYRQEADEATLARLDLERKIESLEEEIRFL RKIHEEEVRELQEQLARQQVHVELDVAKPDLTAALKEIRT QYEAMASSNMHEAEEWYRSKFADLTDAAARNAELLRQAKH EANDYRRQLQSLTCDLESLRGTNESLERQMREQEERHVRE AASYQEALARLEEEGQSLKDEMARHLQEYQDLLNVKLALD IEIATYRKLLEGEENRITIPVQTFSNLQIRETSLDTKSVS EGHLKRNIVVKTVEMRDGEVIKESKQEHKDVM
Sequence Similarities :	Belongs to the intermediate filament family.
Tag :	Non

Gene Name	GFAP glial fibrillary acidic protein [ Homo sapiens ]
Official Symbol	GFAP
Synonyms	GFAP; glial fibrillary acidic protein; FLJ45472; intermediate filament protein;
Gene ID	2670
mRNA Refseq	NM_001131019
Protein Refseq	NP_001124491
MIM	137780
Uniprot ID	P14136
Chromosome Location	17q21
Function	integrin binding; structural constituent of cytoskeleton;

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Cat.No. :	GFAP-29017TH
Product Overview :	Recombinant full length Human GFAP (amino acids 1-432) with a N terminal proprietary tag; predicted MWt 73.59kDa inclusive of tag.

Recombinant Human GFAP