Recombinant Human GAN protein, His & T7-tagged

• Cat.No.: GAN-1614H
• Product Overview: Recombinant Human GAN aa. (Cys30~Gly326 (Accession # Q9H2C0)) fused with N-terminal His & T7 tag was produced in E. coli cells.

Specification

• Description: This gene encodes a member of the cytoskeletal BTB/kelch (Broad-Complex, Tramtrack and Bric a brac) repeat family. The encoded protein plays a role in neurofilament architecture and is involved in mediating the ubiquitination and degradation of some proteins. Defects in this gene are a cause of giant axonal neuropathy (GAN).
• Source: E. coli
• Species: Human
• Tag: His&T7
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 37.4kDa
• Protein length: Cys30~Gly326
• Endotoxin: <1.0EU per 1ug (determined by the LAL method)
• Purity: >90%
• Applications: SDS-PAGE; WB; ELISA; IP.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Storage buffer: Supplied as lyophilized form in PBS, pH7.4, containing 5% trehalose, 0.01% sarcosyl.
• Reconstitution: Reconstitute in sterile PBS, pH7.2-pH7.4.
• Isoelectric Point: 5.1

Gene Information

• Gene Name: GAN gigaxonin [ Homo sapiens (human) ]
• Official Symbol: GAN
• Synonyms: GAN; gigaxonin; GAN1; KLHL16; kelch-like family member 16; kelch-like protein 16
• Gene ID: 8139
• mRNA Refseq: NM_022041.3
• Protein Refseq: NP_071324.1
• UniProt ID: Q9H2C0