Recombinant Human GAB1, His-tagged

• Cat.No.: GAB1-27493TH
• Product Overview: Recombinant full length Human GAB1 with N-terminal His tag expressed in a Baculovirus infected Sf9 cell expression system, MWt 108kDa.

Specification

• Species: Human
• Tag: His
• Description: The protein encoded by this gene is a member of the IRS1-like multisubstrate docking protein family. It is an important mediator of branching tubulogenesis and plays a central role in cellular growth response, transformation and apoptosis. Two transcript variants encoding different isoforms have been found for this gene.
• Conjugation: HIS
• Form: Liquid
• Storage buffer: Preservative: 150mM ImidazoleConstituents: 25% Glycerol, 50mM Sodium phosphate, 300mM Sodium chloride, 2mM DTT, 0.1mM PMSF, pH 7.0
• Storage: Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
• Sequence Similarities: Belongs to the GAB family.Contains 1 PH domain.
• Full Length: Full L.

Gene Information

• Gene Name: GAB1 GRB2-associated binding protein 1 [ Homo sapiens ]
• Official Symbol: GAB1
• Synonyms: GAB1; GRB2-associated binding protein 1; GRB2-associated-binding protein 1
• Gene ID: 2549
• mRNA Refseq: NM_002039
• Protein Refseq: NP_002030
• MIM: 604439
• Uniprot ID: Q13480
• Chromosome Location: 4q31.1
• Pathway: B Cell Receptor Signaling Pathway, organism-specific biosystem; Bacterial invasion of epithelial cells, organism-specific biosystem; Bacterial invasion of epithelial cells, conserved biosystem; Downstream signaling of activated FGFR, organism-specific biosystem; EGF receptor (ErbB1) signaling pathway, organism-specific biosystem
• Function: SH3/SH2 adaptor activity; protein binding