Recombinant Human FYN Oncogene Related To SRC, FGR, YES, His-tagged

• Cat.No.: FYN-2128H
• Product Overview: Recombinant full length human FynT produced ininsect cells is fused to a his-tag.

Specification

• Species: Human
• Source: Insect Cells
• Tag: His
• Description: Fyn, a Src family tyrosine kinase, is important for normal development and function of T lymphocytes. Proto-oncogene tyrosine-protein kinase Fyn is an enzyme that in humans is encoded by the FYN gene.This gene is a member of the protein-tyrosine kinase oncogene family. It encodes a membrane-associated tyrosine kinase that has been implicated in the control of cell growth. The protein associates with the p85 subunit of phosphatidylinositol 3-kinase and interacts with the fyn-binding protein. Alternatively spliced transcript variants encoding distinct isoforms exist.
• Source/Host: insect cells.
• MW: 63 kDa.
• Application: Kinetics and functional studies, phosphorylation of target substrates, drug screening.
• Long Term Storage: -20°C.
• Full Length: Full L.

Gene Information

• Gene Name: FYN FYN oncogene related to SRC, FGR, YES [ Homo sapiens ]
• Synonyms: FYN oncogene related to SRC, FGR, YES; SLK; SYN; MGC45350; FYN; proto-oncogene tyrosine-protein kinase fyn; src-like kinase; Protooncogene Syn; OTTHUMP00000017917; c-syn protooncogene; src/yes-related novel; tyrosine kinase p59fyn(T); p59-Fyn; protein-tyrosine kinase fyn ; OKT3-induced calcium influx regulator; EC 2.7.10.2; OTTHUMP00000017915; OTTHUMP00000017914; src-like kinase
• Gene ID: 2534
• mRNA Refseq: NM_002037
• Protein Refseq: NP_002028
• MIM: 137025
• UniProt ID: P06241
• Chromosome Location: 6q21
• Pathway: Adherens junction; Axon guidance; Fc epsilon RI signaling pathway; Focal adhesion; Natural killer cell mediated cytotoxicity; Pathogenic Escherichia coli infection; Prion diseases; T cell receptor signaling pathway
• Function: non-membrane spanning protein tyrosine kinase activity; ATP binding; glycoprotein binding; identical protein binding; manganese ion binding; metal ion binding; nucleotide binding; transferase activity; tubulin binding