Recombinant Human FTL protein, MYC/DDK-tagged

• Cat.No.: FTL-65H
• Product Overview: Recombinant Human FTL fused with MYC/DDK tag at C-terminal was expressed in HEK293.

Specification

• Species: Human
• Source: HEK293
• Tag: DDK&Myc
• Description: This gene encodes the light subunit of the ferritin protein. Ferritin is the major intracellular iron storage protein in prokaryotes and eukaryotes. It is composed of 24 subunits of the heavy and light ferritin chains. Variation in ferritin subunit composition may affect the rates of iron uptake and release in different tissues. A major function of ferritin is the storage of iron in a soluble and nontoxic state. Defects in this light chain ferritin gene are associated with several neurodegenerative diseases and hyperferritinemia-cataract syndrome. This gene has multiple pseudogenes.
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 19.8 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: FTL ferritin, light polypeptide [ Homo sapiens ]
• Official Symbol: FTL
• Synonyms: FTL; ferritin, light polypeptide; ferritin light chain; ferritin L subunit; ferritin L chain; ferritin light polypeptide like 3; L apoferritin; MGC71996; ferritin L-chain; ferritin light polypeptide-like 3; NBIA3
• Gene ID: 2512
• mRNA Refseq: NM_000146
• Protein Refseq: NP_000137
• MIM: 134790
• UniProt ID: P02792
• Chromosome Location: 19q13.33
• Pathway: Clathrin derived vesicle budding, organism-specific biosystem; Golgi Associated Vesicle Biogenesis, organism-specific biosystem; Iron uptake and transport, organism-specific biosystem; Membrane Trafficking, organism-specific biosystem; Mineral absorption, organism-specific biosystem; Mineral absorption, conserved biosystem; Porphyrin and chlorophyll metabolism, organism-specific biosystem
• Function: ferric iron binding; ferroxidase activity; identical protein binding; iron ion binding; oxidoreductase activity