Native Human Ferritin, Light Polypeptide

• Cat.No.: FTL-673H
• Product Overview: Native Human FTL isprepared from Human Liver.

Specification

• Species: Human
• Source: Human Liver
• Tag: Non
• Description: HumanFTL is a globular protein found mainly in the liver, which can store about4500 iron ions in a hollow shell made of 24 identical subunits. Inside thehuman FTL shell, iron ions form crystallites together with phosphate andhydroxide ions. Human Serum FTL levels are measured in patients as part ofthe iron studies workup for anemia and for restless leg syndrome. Human FTLlevels have a direct correlation with the total amount of iron stored in thebody. Human FTL level(s) are also indicative of the erosion of iron storesduring pregnancy.
• Form: Sodium chloridebuffer, pH 7.5.
• Molecular Weight: 440 kDa
• Purity: > 98%
• Concentration: > 1.0 mg/ml
• Biological Activity: > 1.0 mg/ml
• Storage: Store at 2-4°C.Stable for 2 years from delivery. Avoid repeated freeze-thaw cycles.
• Pathways: Clathrin derived vesicle budding; GolgiAssociated Vesicle Biogenesis; Membrane Trafficking; Mineral absorption;Porphyrin and chlorophyll metabolism; trans-Golgi Network Vesicle Budding

Gene Information

• Gene Name: FTL ferritin, light polypeptide[ Homo sapiens ]
• Official Symbol: FTL
• Synonyms: FTL; ferritin, lightpolypeptide; NBIA3; MGC71996; ferritin, light polypeptide; ferritin Lsubunit; ferritin L-chain; ferritin light chain; ferritin lightpolypeptide-like 3
• Gene ID: 2512
• mRNA Refseq: NM_000146
• Protein Refseq: NP_000137
• MIM: 134790
• UniProt ID: P02792
• Chromosome Location: 19q13.3-q13.4
• Function: binding;ferric iron binding; identical protein binding; iron ion binding;oxidoreductase activity