Recombinant Human FOXR1, His-tagged

• Cat.No.: FOXR1-12989H
• Product Overview: Recombinant Human FOXR1 protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 58-181a.a.
• Description: This gene encodes a member of the forkhead box (FOX) family of transcription factors. FOX family members are monomeric, helix-turn-helix proteins with a core DNA-binding domain of approximately 110 aa. Many FOX transcription factors play roles in determining cell fates during early development. This forkhead box protein lacks the C-terminal basic region found in many other FOX family members. It is located within the 11q23.3 region which is commonly deleted in neuroblastomas.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.

Gene Information

• Gene Name: FOXR1 forkhead box R1 [ Homo sapiens ]
• Official Symbol: FOXR1
• Synonyms: FOXR1; forkhead box R1; forkhead box protein R1; DLNB13; FOXN5; forkhead box protein N5; forkhead box R1 variant 1; MGC149486
• Gene ID: 283150
• mRNA Refseq: NM_181721
• Protein Refseq: NP_859072
• UniProt ID: Q6PIV2
• Chromosome Location: 11q23.3
• Function: DNA binding, bending; double-stranded DNA binding; sequence-specific DNA binding; sequence-specific distal enhancer binding RNA polymerase II transcription factor activity; transcription factor binding