Recombinant Human FOSB Protein, His-tagged

• Cat.No.: FOSB-01H
• Product Overview: Purified recombinant protein of Human FBJ murine osteosarcoma viral oncogene homolog B (FOSB), transcript variant 1,Met1-Leu255, with N-terminal His tag, expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 1-255 a.a.
• Description: The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
• Molecular Mass: 27.3 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: > 50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol,1% Sarkosyl.

Gene Information

• Gene Name: FOSB FosB proto-oncogene, AP-1 transcription factor subunit [ Homo sapiens (human) ]
• Official Symbol: FOSB
• Synonyms: FOSB; FosB proto-oncogene, AP-1 transcription factor subunit; AP-1; G0S3; GOS3; GOSB; protein FosB; FBJ murine osteosarcoma viral oncogene homolog B; FosB proto-oncogene, AP-1 trancription factor subunit; G0/G1 switch regulatory protein 3; activator protein 1; transcription factor AP-1 subunit FosB
• Gene ID: 2354
• mRNA Refseq: NM_006732
• Protein Refseq: NP_006723
• MIM: 164772
• UniProt ID: P53539