Recombinant Human FGF18 Protein (28-207), N-hFc-tagged

• Cat.No.: FGF18-12H
• Product Overview: Recombinant human FGF-18 protein (aa 28-207) fused to the N-terminus of the Fc region of human IgG1 was expressed in HEK293.

Specification

• Species: Human
• Source: HEK293
• Tag: Fc
• Protein Length: 28-207
• Description: The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion. It has been shown in vitro that this protein is able to induce neurite outgrowth in PC12 cells. Studies of the similar proteins in mouse and chick suggested that this protein is a pleiotropic growth factor that stimulates proliferation in a number of tissues, most notably the liver and small intestine. Knockout studies of the similar gene in mice implied the role of this protein in regulating proliferation and differentiation of midline cerebellar structures.
• Molecular Mass: ~60 kDa (SDS-PAGE)
• Endotoxin: <5 EU/mg purified protein (LAL test; Lonza).
• Purity: ≥ 98% (SDS-PAGE)
• Stability: Stable for at least 1 year after receipt when stored at -20 centigrade.
  Working aliquots are stable for up to 3 months when stored at -20 centigrade.
• Storage: Short Term Storage: +4 centigrade
  Long Term Storage: -20 centigrade
• Storage Buffer: Lyophilized from 0.2 μm-filtered solution in PBS.
• Reconstitution: Reconstitute 50 μg vial in 50 μL sterile water to a concentration of 1 mg/mL.
  Add 1 × PBS to the desired protein concentration.
• Handling: After opening, prepare aliquots and store at -20 centigrade.
  Avoid freeze/thaw cycles.
  Centrifuge lyophilized vial before opening and reconstitution.
• Shipping: BLUE ICE

Gene Information

• Gene Name: FGF18 fibroblast growth factor 18 [ Homo sapiens (human) ]
• Official Symbol: FGF18
• Synonyms: FGF18; fibroblast growth factor 18; ZFGF5; FGF-18; fibroblast growth factor 18
• Gene ID: 8817
• mRNA Refseq: NM_003862.3
• Protein Refseq: NP_003853.1
• MIM: 603726
• UniProt ID: O76093