Recombinant Human Fc Fragment Of LgE, Low Affinity II, Receptor For (CD23)

• Cat.No.: FCER2-4261H
• Product Overview: CD23 Human Recombinant (aa 48-248) expressed in E.coli, shows a 48 kDa band on SDS-PAGE. The CD23 is purified by proprietary chromatographic techniques.

Specification

• Species: Human
• Source: Human
• Tag: Non
• Protein Length: 48-248 a.a.
• Description: CD23 is a 45kDa glycoprotein, which is present on a subpopulation of freshly isolated peripheral blood and tonsil B cells and strongly expressed on EBV-transformed B lymphoblasts. The CD23 molecule is identical to the low affinity IgE receptor found on B cells. Expression of CD23 has been detected in neoplastic cells from cases of B cell chronic lymphocyctic leukaemia and some cases of centroblastic/centrocytic lymphoma.
• Form: CD23 at 100µg/ml in 50mM Tris-Acetate, pH7.5, 1mM EDTA and 20% Glycerol.
• Physical Appearance: Sterile Filtered clear solution.
• Storage: Store vial at -20°C to -80°C. When stored at the recommended temperature, this protein is stable for 12 months. Please prevent freeze-thaw cycles.

Gene Information

• Gene Name: FCER2 Fc fragment of IgE, low affinity II, receptor for (CD23) [ Homo sapiens ]
• Official Symbol: FCER2
• Synonyms: FCER2; Fc fragment of IgE, low affinity II, receptor for (CD23); CD23; FCE2; CD23A; IGEBF; CLEC4J; low affinity immunoglobulin epsilon Fc receptor; BLAST-2; CD23 antigen; fc-epsilon-RII; lymphocyte IgE receptor; immunoglobulin E-binding factor; C-type lectin domain family 4 member J; C-type lectin domain family 4, member J; Low affinity immunoglobulin epsilon Fc receptor; Fc-epsilon-RII; Immunoglobulin E-binding factor; Lymphocyte IgE receptor; Fc fragment of IgE, low affinity II, receptor for (CD23A)
• Gene ID: 2208
• mRNA Refseq: NM_001207019
• Protein Refseq: NP_001193948
• MIM: 151445
• UniProt ID: P06734
• Chromosome Location: 19p13.3
• Pathway: Hematopoietic cell lineage; IL-3 Signaling Pathway; IL4-mediated signaling events
• Function: IgE binding; binding; integrin binding; metal ion binding; receptor activity; sugar binding