Recombinant Human FBXO17, His-tagged

• Cat.No.: FBXO17-12786H
• Product Overview: Recombinant Human FBXO17 protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 1-278a.a.
• Description: This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and it contains an F-box domain. Alternative splicing of this gene results in 2 transcript variants encoding different isoforms.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.

Gene Information

• Gene Name: FBXO17 F-box protein 17 [ Homo sapiens ]
• Official Symbol: FBXO17
• Synonyms: FBXO17; F-box protein 17; F box only protein 17 , FBXO26; F-box only protein 17; F box only protein 26; FBG4; Fbx17; FLJ11798; FLJ25205; MGC9379; F-box protein FBG4; F-box only protein 26; FBX26; FBXO26; FLJ58300
• Gene ID: 115290
• mRNA Refseq: NM_024907
• Protein Refseq: NP_079183
• MIM: 609094
• UniProt ID: Q96EF6
• Chromosome Location: 19q13.2
• Pathway: Adaptive Immune System, organism-specific biosystem; Antigen processing: Ubiquitination & Proteasome degradation, organism-specific biosystem; Class I MHC mediated antigen processing & presentation, organism-specific biosystem; Immune System, organism-specific biosystem; Selenium Metabolism and Selenoproteins, organism-specific biosystem
• Function: glycoprotein binding; protein binding