FBXO17
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Official Full Name
F-box protein 17 -
Overview
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and it contains an F-box domain. Alternative splicing of this gene results in 2 transcript variants encoding different isoforms -
Synonyms
FBXO17;F-box only protein 17;F-box protein FBG4;F-box only protein 26;F-box protein 17;FBXO26;FBG4;FLJ58300;FBX17;FLJ25205;FLJ11798;FBX26
Recombinant Proteins
- Human
- Rat
- E.coli
- Mammalian Cells
- Wheat Germ
- HEK293
- In Vitro Cell Free System
- His
- GST
- Non
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| FBXO17-12786H | Recombinant Human FBXO17, His-tagged | E.coli | Human | His | 1-278a.a. | |
| FBXO17-2289R | Recombinant Rat FBXO17 Protein | Mammalian Cells | Rat | His |
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| FBXO17-3917H | Recombinant Human FBXO17 Protein, GST-tagged | Wheat Germ | Human | GST |
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| FBXO17-6307HCL | Recombinant Human FBXO17 293 Cell Lysate | HEK293 | Human | Non |
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| FBXO17-1946R | Recombinant Rat FBXO17 Protein, His (Fc)-Avi-tagged | HEK293 | Rat | His&Fc&Avi |
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| FBXO17-1946R-B | Recombinant Rat FBXO17 Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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| FBXO17-5023HF | Recombinant Full Length Human FBXO17 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 287 amino acids |
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Involved Pathway
FBXO17 involved in several pathways and played different roles in them. We selected most pathways FBXO17 participated on our site, such as Adaptive Immune System,Antigen processing: Ubiquitination &,Proteasome degradation, which may be useful for your reference. Also, other proteins which involved in the same pathway with FBXO17 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Class I MHC mediated antigen processing & | UBE2F,ASB13,TRIM63,HECTD3,UBE2U,UBR1,SPSB2,ASB14,KLHL21,UBE2L6 |
| Selenium Metabolism and Selenoproteins | SP3,CREM,TRNAU1AP,MSRB1,TXNRD2,SELT,SELK,SELENBP1,DIO2,TXNRD3IT1 |
| Proteasome degradation | ASB8,UBE2U,TRIM9,TRIM50,ASB10,RNF138,TPP2,TRIM69,ASB7,SPSB4 |
| presentation | VPRBP,LRSAM1,ARIH2,ERAP2,LRRC41,UFL1,CTSL2,ASB6,CYBB,SEC23A |
| Antigen processing: Ubiquitination & | RNF6,ASB7,ASB6,VPRBP,RNF144B,RNF41,WWP1,SH3RF1,LRRC41,UBA5 |
| Adaptive Immune System | CD300A,ASB11,UFL1,FGF8B,MGC174857,MKRN1,THEM4,ERAP2,LILRA1,PTBP3 |
| Immune System | IRF9,ASB2,DEFA6,AF251705,LILRB4,LY86,RNF135,HECTD3,LAIR2,DYNC1I1 |
Protein Function
FBXO17 has several biochemical functions, for example, glycoprotein binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by FBXO17 itself. We selected most functions FBXO17 had, and list some proteins which have the same functions with FBXO17. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | ARL13B,GRAMD3,CA,RNF139,MOB4,CC10,HDGFRP2,C4orf33,DAK,CWC22 |
| glycoprotein binding | DNAJA2,CANX,Serpina1c,SDC1,DNAJC5,CSNK1D,FLNA,THBS1,RASA1,SERPINA1A |
Interacting Protein
FBXO17 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FBXO17 here. Most of them are supplied by our site. Hope this information will be useful for your research of FBXO17.
SKP1;COPS6;COPS5
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