Recombinant Human EXOSC1 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: EXOSC1-1060H
• Product Overview: EXOSC1 MS Standard C13 and N15-labeled recombinant protein (NP_057130) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene encodes a core component of the exosome. The mammalian exosome is required for rapid degradation of AU rich element-containing RNAs but not for poly(A) shortening. The association of this protein with the exosome is mediated by protein-protein interactions with ribosomal RNA-processing protein 42 and ribosomal RNA-processing protein 46. Alternative splicing of this gene results in multiple transcript variants.
• Source: HEK293
• Species: Human
• Tag: Myc&DDK
• Molecular Mass: 21.5 kDa
• AA Sequence: MAPPVRYCIPGERLCNLEEGSPGSGTYTRHGYIFSSLAGCLMKSSENGALPVVSVVRETESQLLPDVGAIVTCKVSSINSRFAKVHILYVGSMPLKNSFRGTIRKEDVRATEKDKVEIYKSFRPGDIVLAKVISLGDAQSNYLLTTAENELGVVVAHSESGIQMVPISWCEMQCPKTHTKEFRKVARVQPEFLQTTRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: EXOSC1 exosome component 1 [ Homo sapiens (human) ]
• Official Symbol: EXOSC1
• Synonyms: EXOSC1; exosome component 1; exosome complex component CSL4; CGI 108; CSL4; CSL4 exosomal core protein homolog (yeast); Csl4p; hCsl4p; p13; SKI4; Ski4p; exosomal core protein CSL4; 3-5 exoribonuclease CSL4 homolog; CSL4 exosomal core protein homolog; homolog of yeast exosomal core protein CSL4; CGI-108; RP11-452K12.9
• Gene ID: 51013
• mRNA Refseq: NM_016046
• Protein Refseq: NP_057130
• MIM: 606493
• UniProt ID: Q9Y3B2