Recombinant Human ERN2 protein, His-tagged

• Cat.No.: ERN2-677H
• Product Overview: Recombinant Human ERN2(aa 452-926) fused with His tag was expressed in HEK293.

Specification

• Species: Human
• Source: HEK293
• Tag: His
• Protein Length: aa 452-926
• Form: Tris-based buffer,50% glycerol
• AA Sequence: RQQQPQVVE KQQETPLAPA DFAHISQDAQ SLHSGASRRS QKRLQSPSKQ AQPLDDPEAE QLTVVGKISF NPKDVLGRGA GGTFVFRGQF EGRAVAVKRL LRECFGLVRR EVQLLQESDR HPNVLRYFCT ERGPQFHYIA LELCRASLQE YVENPDLDRG GLEPEVVLQQ LMSGLAHLHS LHIVHRDLKP GNILITGPDS QGLGRVVLSD FGLCKKLPAG RCSFSLHSGI PGTEGWMAPE LLQLLPPDSP TSAVDIFSAG CVFYYVLSGG SHPFGDSLYR QANILTGAPC LAHLEEEVHD KVVARDLVGA MLSPLPQPRP SAPQVLAHPF FWSRAKQLQF FQDVSDWLEK ESEQEPLVRA LEAGGCAVVR DNWHEHISMP LQTDLRKFRS YKGTSVRDLL RAVRNKKHHY RELPVEVRQA LGQVPDGFVQ YFTNRFPRLL LHTHRAMRSC ASESLFLPYY PPDSEARRPC PGATGR
• Purity: >90% ( SDS-PAGE )
• Storage: Store at -20 centigrade, for extended storage, conserve at -20 centigrade or -80 centigrade. Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week.

Gene Information

• Gene Name: ERN2 endoplasmic reticulum to nucleus signaling 2 [ Homo sapiens ]
• Official Symbol: ERN2
• Synonyms: ERN2; endoplasmic reticulum to nucleus signaling 2; ER to nucleus signalling 2; serine/threonine-protein kinase/endoribonuclease IRE2; IRE1b; hIRE2p; IRE1 beta; inositol-requiring 1 beta; inositol-requiring protein 2; IRE1, S. cerevisiae, homolog of; endoplasmic reticulum-to-nucleus signaling 2; endoplasmic reticulum to nucleus signalling 2; IRE1-BETA
• Gene ID: 10595
• mRNA Refseq: NM_033266
• Protein Refseq: NP_150296
• MIM: 604034
• UniProt ID: Q76MJ5
• Chromosome Location: 16p12.2
• Function: ATP binding; endonuclease activity; endoribonuclease activity, producing 5-phosphomonoesters; hydrolase activity; magnesium ion binding; nucleotide binding; protein serine/threonine kinase activity