Recombinant Human EREG protein, His & GST-tagged

• Cat.No.: EREG-1998H
• Product Overview: Recombinant Human EREG aa. (Val30~Val169 (Accession # O14944)) fused with N-terminal His & GST tag was produced in E. coli cells.

Specification

• Description: This gene encodes a secreted peptide hormone and member of the epidermal growth factor (EGF) family of proteins. The encoded protein is a ligand of the epidermal growth factor receptor (EGFR) and the structurally related erb-b2 receptor tyrosine kinase 4 (ERBB4). The encoded protein may be involved in a wide range of biological processes including inflammation, wound healing, oocyte maturation, and cell proliferation. Additionally, the encoded protein may promote the progression of cancers of various human tissues.
• Source: E. coli
• Species: Human
• Tag: His&GST
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 48.3kDa
• Protein length: Val30~Val169
• Endotoxin: <1.0EU per 1ug (determined by the LAL method)
• Purity: > 95%
• Characteristic: The isoelectric point is 6.4.
• Applications: SDS-PAGE; WB; ELISA; IP.
• Stability: The thermal stability is described by the loss rate of the target protein. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. (Referring from China Biological Products Standard, which was calculated by the Arrhenius equation.) The loss of this protein is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Storage Buffer: Supplied as lyophilized form in PBS, pH7.4, containing 5% sucrose, 0.01% sarcosyl.
• Reconstitution: Reconstitute in sterile PBS, pH7.2-pH7.4.

Gene Information

• Gene Name: EREG epiregulin [ Homo sapiens (human) ]
• Official Symbol: EREG
• Synonyms: Ptpn13; protein tyrosine phosphatase, non-receptor type 13; RIP; PTPL1; Ptpri; PTP-BL; AI324989; tyrosine-protein phosphatase non-receptor type 13; PTP36; protein tyrosine phosphatase DPZPTP; protein tyrosine phosphatase PTP-BL; protein-tyrosine phosphatase RIP; tyrosine phosphatase
• Gene ID: 2069
• mRNA Refseq: NM_001432.2
• Protein Refseq: NP_001423.1
• UniProt ID: O14944