EREG
-
Official Full Name
epiregulin -
Overview
Epiregulin (EPR) is a protein that in humans is encoded by the EREG gene. -
Synonyms
Epiregulin;EPR;EREG;ER;Ereg;epiregulin;proepiregulin
Recombinant Proteins
- Mouse
- Human
- Chicken
- Rat
- HEK293
- E.coli
- Mammalian Cell
- Wheat Germ
- Human Cell
- In Vitro Cell Free System
- E.coli expression system
- Fc
- His
- Non
- His&GST
- His&T7
- GST
- His&SUMO
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| Ereg-576M |
Active Recombinant Mouse Ereg, Fc tagged
|
HEK293 | Mouse | Fc | Val 56-Leu 101 | |
| EREG-562H | Active Recombinant Human EREG protein(Val63-Leu108), hFc-tagged | HEK293 | Human | Fc | Val63-Leu108 | |
| Ereg-595M |
Active Recombinant Mouse Ereg
|
E.coli | Mouse | Val56-Leu101 |
|
|
| EREG-1077C | Recombinant Chicken EREG | Mammalian Cell | Chicken | His |
|
|
| Ereg-198M | Recombinant Mouse Epiregulin | E.coli | Mouse | Non |
|
|
| EREG-1998H | Recombinant Human EREG protein, His & GST-tagged | E.coli | Human | His&GST | Val30~Val169 |
|
| Ereg-1999R | Recombinant Rat Ereg protein, His & T7-tagged | E.coli | Rat | His&T7 | Met1~Val162 |
|
| EREG-235H | Recombinant Human EREG protein | E.coli | Human | Non | 49 |
|
| EREG-28692TH | Recombinant Human EREG | E.coli | Human | Non | 49 amino acids |
|
| EREG-3465H | Recombinant Human EREG Protein, GST-tagged | Wheat Germ | Human | GST |
|
|
| EREG-1868HCL | Recombinant Human EREG cell lysate | Human Cell | Human | Non |
|
|
| EREG-1871MCL | Recombinant Mouse EREG cell lysate | Human Cell | Mouse | Non |
|
|
| EREG-001H | Recombinant Human EREG Protein, His-tagged | HEK293 | Human | His | 63-108 aa |
|
| EREG-004H | Active Recombinant Human EREG Protein | E.coli | Human | 19-496 a.a. |
|
|
| EREG-023H | Active Recombinant Human EREG Protein | E.coli | Human | 63-108 a.a. |
|
|
| EREG-125E | Active Recombinant Human EREG Protein (50 aa) | E.coli | Human | 50 |
|
|
| EREG-1438H | Recombinant Human EREG Protein, His-tagged | E.coli | Human | His | Val63-Leu108 |
|
| EREG-2869H | Recombinant Human EREG protein, His-SUMO-tagged | E.coli | Human | His&SUMO | 60-119aa |
|
| EREG-4564HF | Recombinant Full Length Human EREG Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 169 amino acids |
|
| RFL19531HF | Recombinant Full Length Human Proepiregulin(Ereg) Protein, His-Tagged | E.coli expression system | Human | His | Full L. Full Length of Mature Protein (30-169) |
|
Involved Pathway
EREG involved in several pathways and played different roles in them. We selected most pathways EREG participated on our site, such as ErbB signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with EREG were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| ErbB signaling pathway | GSK3AA,BADB,CAMK2D,PTK2AA,RAF1B,MAP2K2B,CAMK2G1,MAPK10,GSK3B,BRAF |
Protein Function
EREG has several biochemical functions, for example, epidermal growth factor receptor binding,growth factor activity,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by EREG itself. We selected most functions EREG had, and list some proteins which have the same functions with EREG. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| epidermal growth factor receptor binding | SHC1,TNK2,VAV3,EFEMP1,ATXN2,HBEGF,ARF4,ERBB4,SOCS5,MS4A1 |
| protein binding | PLDN,CD93,ARVCF,SIKE1,SETDB2,PHF21A,RAD1,ATOX1,MMS22L,CCDC70 |
| growth factor activity | GPR19,NRTN,HBEGFA,INHA,IL8L2,TGFB1A,NTF4,LACRT,BMP4,GDF2 |
Interacting Protein
EREG has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with EREG here. Most of them are supplied by our site. Hope this information will be useful for your research of EREG.
Resources
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References
- Addison, JB; Koontz, C; et al. KAP1 Promotes Proliferation and Metastatic Progression of Breast Cancer Cells. CANCER RESEARCH 75:344-355(2015).
- Takahashi, N; Yamada, Y; et al. Serum levels of hepatocyte growth factor and epiregulin are associated with the prognosis on anti-EGFR antibody treatment in KRAS wild-type metastatic colorectal cancer. BRITISH JOURNAL OF CANCER 110:2716-2727(2014).
