Recombinant Human EPH Receptor B3, GST-tagged, Active

• Cat.No.: EPHB3-305H
• Product Overview: Recombinant human EPHB3 (585-end) was expressed by baculovirus inSf9 insect cellsusing an N-terminal GST tag. MW=68kDa.

Specification

• Species: Human
• Source: Sf9 Cells
• Tag: GST
• Protein Length: 585-end a.a.
• Description: EPHB3 is a member of the Ephrin receptor family and is expressed during embryonic development in multiple regions of the central nervous system. In adult brain, EPHB3 is expressed in the cerebellum, raphe pallidus, hippocampus, entorhinal cortex, and both motor and sensory cortices. EPHB3 is involved in the maintenance of mature neuronal connections and/or re-arrangement of synaptic connections during late stages of development. EPHB3 plays a role in the regulation of cell adhesion and migration, and the catalytic activity of EPHB3 is required for inhibition of integrin-mediated cell adhesion.
• Sequence: 585-end.
• Applications: Kinase Assay, Western Blot.
• Storage And Stability: Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

Gene Information

• Gene Name: EPHB3 EPH receptor B3 [ Homo sapiens ]
• Synonyms: EPHB3; EPH receptor B3;ETK2; HEK2; TYRO6; ephrin receptor EphB3; human embryo kinase 2; EPH-like tyrosine kinase-2; EC 2.7.10.1
• Gene ID: 2049
• mRNA Refseq: NM_004443
• Protein Refseq: NP_004434
• MIM: 601839
• UniProt ID: P54753
• Chromosome Location: 3q21-qter
• Pathway: Axon guidance
• Function: ATP binding; axon guidance receptor activity; nucleotide binding; receptor activity; receptor binding; transferase activity; transmembrane-ephrin receptor activity