Recombinant Human ELP4, His-tagged

• Cat.No.: ELP4-12425H
• Product Overview: Recombinant Human ELP4 protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: C-term-299a.a.
• Description: This gene encodes a component of the six subunit elongator complex, a histone acetyltransferase complex that associates directly with RNA polymerase II during transcriptional elongation. The human gene can partially complement sensitivity phenotypes of yeast ELP4 deletion mutants. Alternatively spliced variants that encode different protein isoforms have been described but the full-length nature of only one has been determined.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.

Gene Information

• Gene Name: ELP4 elongation protein 4 homolog (S. cerevisiae) [ Homo sapiens ]
• Official Symbol: ELP4
• Synonyms: ELP4; elongation protein 4 homolog (S. cerevisiae); C11orf19, chromosome 11 open reading frame 19; elongator complex protein 4; PAXNEB; hELP4; PAX6 neighbor gene protein; PAX6NEB; C11orf19; dJ68P15A.1; FLJ20498
• Gene ID: 26610
• mRNA Refseq: NM_019040
• Protein Refseq: NP_061913
• MIM: 606985
• UniProt ID: Q96EB1
• Chromosome Location: 11p13
• Function: contributes_to histone acetyltransferase activity; phosphorylase kinase regulator activity; protein binding