Recombinant Human EIF5A2 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: EIF5A2-4318H
• Product Overview: EIF5A2 MS Standard C13 and N15-labeled recombinant protein (NP_065123) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: mRNA-binding protein involved in translation elongation. Has an important function at the level of mRNA turnover, probably acting downstream of decapping. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. Functions as a regulator of apoptosis. Mediates effects of polyamines on neuronal process extension and survival. May play an important role in brain development and function, and in skeletal muscle stem cell differentiation.
• Source: HEK293
• Species: Human
• Tag: Myc&DDK
• Molecular Mass: 16.8 kDa
• AA Sequence: MADEIDFTTGDAGASSTYPMQCSALRKNGFVVLKGRPCKIVEMSTSKTGKHGHAKVHLVGIDIFTGKKYEDICPSTHNMDVPNIKRNDYQLICIQDGYLSLLTETGEVREDLKLPEGELGKEIEGKYNAGEDVQVSVMCAMSEEYAVAIKPCKTRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: EIF5A2 eukaryotic translation initiation factor 5A2 [ Homo sapiens (human) ]
• Official Symbol: EIF5A2
• Synonyms: EIF5A2; eukaryotic translation initiation factor 5A2; eukaryotic translation initiation factor 5A-2; eIF-5A-2; eukaryotic initiation factor 5A; EIF-5A2; eIF5AII
• Gene ID: 56648
• mRNA Refseq: NM_020390
• Protein Refseq: NP_065123
• MIM: 605782
• UniProt ID: Q9GZV4