EIF5A2
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Official Full Name
eukaryotic translation initiation factor 5A2 -
Overview
Eukaryotic translation initiation factor 5A-2 is a protein that in humans is encoded by the EIF5A2 gene. -
Synonyms
EIF5A2;eukaryotic translation initiation factor 5A2;eukaryotic translation initiation factor 5A-2;eIF 5A 2;eIF 5A2;eIF5AII;Eukaryotic initiation factor 5A isoform 2;9630038B20;eIF-4D;eIF-5A-2;eIF-5A2;EIF5A 2;IF5A2_HUMAN;MGC124092;MGC124093;OTTHUMP00000213742;OTTHUMP00000213744;OTTHUMP00000213745;eukaryotic initiation factor 5A
Recombinant Proteins
- Human
- Zebrafish
- Rhesus macaque
- Chicken
- Mouse
- E.coli
- Mammalian Cell
- Wheat Germ
- HEK293
- HEK293T
- In Vitro Cell Free System
- GST
- His
- Fc
- Non
- His&Fc&Avi
- Myc&DDK
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| EIF5A2-12389H | Recombinant Human EIF5A2, GST-tagged | E.coli | Human | GST | 1-153a.a. | |
| EIF5A2-12459Z | Recombinant Zebrafish EIF5A2 | Mammalian Cell | Zebrafish | His |
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| EIF5A2-1434R | Recombinant Rhesus monkey EIF5A2 Protein, His-tagged | Mammalian Cell | Rhesus macaque | His |
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| EIF5A2-238H | Recombinant Human EIF5A2, His tagged | E.coli | Human | Fc | 1-153 a.a. |
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| EIF5A2-27178TH | Recombinant Human EIF5A2, His-tagged | E.coli | Human | His | 153 amino acids |
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| EIF5A2-3215H | Recombinant Human EIF5A2 Protein, GST-tagged | Wheat Germ | Human | GST |
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| EIF5A2-7080C | Recombinant Chicken EIF5A2 | Mammalian Cell | Chicken | His |
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| EIF5A2-6640HCL | Recombinant Human EIF5A2 293 Cell Lysate | HEK293 | Human | Non |
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| EIF5A2-1258R | Recombinant Rhesus Macaque EIF5A2 Protein, His (Fc)-Avi-tagged | HEK293 | Rhesus macaque | His&Fc&Avi |
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| EIF5A2-1258R-B | Recombinant Rhesus Macaque EIF5A2 Protein Pre-coupled Magnetic Beads | HEK293 | Rhesus macaque |
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| EIF5A2-1278H | Recombinant Human EIF5A2 protein, His-tagged | E.coli | Human | His | Met1-Lys153 |
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| Eif5a2-2793M | Recombinant Mouse Eif5a2 Protein, Myc/DDK-tagged | HEK293T | Mouse | Myc&DDK |
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| EIF5A2-3580H | Recombinant Human EIF5A2 Protein (Met1-Lys153), N-His tagged | E.coli | Human | His | Met1-Lys153 |
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| EIF5A2-4301HF | Recombinant Full Length Human EIF5A2 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 153 amino acids |
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| EIF5A2-4318H | Recombinant Human EIF5A2 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Human | Myc&DDK |
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Involved Pathway
EIF5A2 involved in several pathways and played different roles in them. We selected most pathways EIF5A2 participated on our site, such as Gamma carboxylation, hypusine formation and arylsulfatase activation,Hypusine synthesis from eIF5A-lysine,Metabolism of proteins, which may be useful for your reference. Also, other proteins which involved in the same pathway with EIF5A2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Hypusine synthesis from eIF5A-lysine | EIF5A,DHPS,DOHH |
| Metabolism of proteins | PHC1,GATA6,MCFD2,TMED10,MUC5AC,IGFBP5,NAT8,MGAT4A,DPH2,EIF2B1 |
| Gamma carboxylation, hypusine formation and arylsulfatase activation | GAS6,PROCA,ARSF,WDR85,DPH2,ARSE,DHPS,OTOP2,EEF2,ARSD |
| Post-translational protein modification | PREB,ADAMTS15,DAD1,SEC23IP,SEC16B,DPH5,ARSJ,SPON1A,STT3A,NAPAB |
Protein Function
EIF5A2 has several biochemical functions, for example, protein binding,ribosome binding,translation elongation factor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by EIF5A2 itself. We selected most functions EIF5A2 had, and list some proteins which have the same functions with EIF5A2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| ribosome binding | RPSA,RPN2,PPP1R2P9,HSPA5,EIF2S1,OLA1,NARG1,MTOR,ETF1,EIF2S1B |
| protein binding | KCNE3,CDHR1,VPS29,GTF2E2,GRIN1,UBE2D2,DDAH2,ELOVL6,KIF20B,FAM107A |
| translation elongation factor activity | GFM1,EEF1D,EEF2A.1,EEF1DA,EEF1A1,EEFSEC,EEF1E1,EEF1A1L1,EEF1B2,EEF2A.2 |
Interacting Protein
EIF5A2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with EIF5A2 here. Most of them are supplied by our site. Hope this information will be useful for your research of EIF5A2.
DHPS;SDCBP;REL;NIF3L1;CDC23;RAB30;PTBP2;NS;DCC
Resources
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References
- Fujimura, K; Wright, T; et al. A Hypusine-eIF5A-PEAK1 Switch Regulates the Pathogenesis of Pancreatic Cancer. CANCER RESEARCH 74:6671-6681(2014).
- Tsang, FH; Au, V; et al. Prognostic Marker MicroRNA-125b Inhibits Tumorigenic Properties of Hepatocellular Carcinoma Cells Via Suppressing Tumorigenic Molecule eIF5A2. DIGESTIVE DISEASES AND SCIENCES 59:2477-2487(2014).
