Recombinant Human EIF4E Protein, GST-tagged
Cat.No. : | EIF4E-3198H |
Product Overview : | Human EIF4E full-length ORF ( AAH12611, 1 a.a. - 217 a.a.) recombinant protein with GST-tag at N-terminal. |
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Species : | Human |
Source : | Wheat Germ |
Tag : | GST |
Description : | The protein encoded by this gene is a component of the eukaryotic translation initiation factor 4F complex, which recognizes the 7-methylguanosine cap structure at the 5' end of messenger RNAs. The encoded protein aids in translation initiation by recruiting ribosomes to the 5'-cap structure. Association of this protein with the 4F complex is the rate-limiting step in translation initiation. This gene acts as a proto-oncogene, and its expression and activation is associated with transformation and tumorigenesis. Several pseudogenes of this gene are found on other chromosomes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015] |
Molecular Mass : | 49.61 kDa |
AA Sequence : | MATVEPETTPTPNPPTTEEEKTESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFDTVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLNRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENREAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV |
Applications : | Enzyme-linked Immunoabsorbent Assay Western Blot (Recombinant protein) Antibody Production Protein Array |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name | EIF4E eukaryotic translation initiation factor 4E [ Homo sapiens ] |
Official Symbol | EIF4E |
Synonyms | EIF4E; eukaryotic translation initiation factor 4E; EIF4EL1, EIF4F; EIF4E1; eIF-4E; eIF-4F 25 kDa subunit; mRNA cap-binding protein; eukaryotic translation initiation factor 4E-like 1; CBP; EIF4F; EIF4EL1; MGC111573; |
Gene ID | 1977 |
mRNA Refseq | NM_001130678 |
Protein Refseq | NP_001124150 |
MIM | 133440 |
UniProt ID | P06730 |
◆ Recombinant Proteins | ||
EIF4E-1428R | Recombinant Rhesus monkey EIF4E Protein, His-tagged | +Inquiry |
EIF4E-39H | Recombinant Human EIF4E Protein (1-217), N-His tagged | +Inquiry |
EIF4E-41H | Recombinant Human EIF4E Protein Complexed With m7GTP (1-217) | +Inquiry |
EIF4E-1252R | Recombinant Rhesus Macaque EIF4E Protein, His (Fc)-Avi-tagged | +Inquiry |
EIF4E-2050H | Recombinant Human EIF4E protein | +Inquiry |
◆ Cell & Tissue Lysates | ||
EIF4E-6651HCL | Recombinant Human EIF4E 293 Cell Lysate | +Inquiry |
Not For Human Consumption!
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