Recombinant Human EIF4E Protein, His tagged, Biotinylated

• Cat.No.: EIF4E-2775HB
• Product Overview: Recombinant human EIF4E protein (1-217 aa), fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. Purified protein was labeled with biotin in vitro

Specification

• Species: Human
• Source: E.coli
• Tag: His&Non
• Protein Length: 1-217 aa
• Description: The protein encoded by this gene is a component of the eukaryotic translation initiation factor 4F complex, which recognizes the 7-methylguanosine cap structure at the 5' end of messenger RNAs. The encoded protein aids in translation initiation by recruiting ribosomes to the 5'-cap structure. Association of this protein with the 4F complex is the rate-limiting step in translation initiation. This gene acts as a proto-oncogene, and its expression and activation is associated with transformation and tumorigenesis. Several pseudogenes of this gene are found on other chromosomes. Alternative splicing results in multiple transcript variants.
• Form: Liquid
• Molecular Mass: 27.2 kDa
• AASequence: MGSSHHHHHH SSGLVPRGSH MATVEPETTP TPNPPTTEEE KTESNQEVAN PEHYIKHPLQ NRWALWFFKN DKSKTWQANL RLISKFDTVEDFWALYNHIQ LSSN LM PG CD YSLFKDGIEP MWEDEKNKRG GRWLITLNKQ QRRSDLDRFW LET LLCLIGE SFDDYSDDVC GAVVNVRAKG DKIAIWTTEC ENREAVTHIG RVYKERLGLPPKIV IGYQSH ADTATKSGST TKNRFVV
• Purity: > 85% by SDS - PAGE
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
• Storage Buffer: PBS buffer
• Concentration: 0.25 mg/ml

Gene Information

• Gene Name: EIF4E eukaryotic translation initiation factor 4E [ Homo sapiens (human) ]
• Official Symbol: EIF4E
• Synonyms: EIF4E; eukaryotic translation initiation factor 4E; CBP; EIF4F; AUTS19; EIF4E1; eIF-4E; EIF4EL1; eukaryotic translation initiation factor 4E; eIF-4F 25 kDa subunit; eukaryotic translation initiation factor 4E-like 1; mRNA cap-binding protein
• Gene ID: 1977
• mRNA Refseq: NM_001130678
• Protein Refseq: NP_001124150
• MIM: 133440
• UniProt ID: P06730