Recombinant Human EIF2AK1 cell lysate

• Cat.No.: EIF2AK1-538HCL

Specification

• Species: Human
• Tag: Non
• Description: The protein encoded by this gene acts at the level of translation initiation to downregulate protein synthesis in response to stress. The encoded protein is a kinase that can be inactivated by hemin. Two transcript variants encoding different isoforms have been found for this gene.
• Size: 100 ul
• Storage Buffer: 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
• Applications: Western Blot

Gene Information

• Gene Name: EIF2AK1 eukaryotic translation initiation factor 2-alpha kinase 1 [ Homo sapiens ]
• Official Symbol: EIF2AK1
• Synonyms: EIF2AK1; eukaryotic translation initiation factor 2-alpha kinase 1; heme regulated initiation factor 2 alpha kinase; HRI; KIAA1369; heme-regulated inhibitor; heme-regulated repressor; heme-controlled repressor; heme sensitive initiation factor 2a kinase; heme-regulated initiation factor 2-alpha kinase; hemin-sensitive initiation factor 2-alpha kinase; heme-regulated eukaryotic initiation factor eIF-2-alpha kinase; HCR
• Gene ID: 27102
• mRNA Refseq: NM_001134335
• Protein Refseq: NP_001127807
• MIM: 613635
• UniProt ID: Q9BQI3
• Chromosome Location: 7p22
• Pathway: Hepatitis C, organism-specific biosystem; Hepatitis C, conserved biosystem; Herpes simplex infection, organism-specific biosystem; Herpes simplex infection, conserved biosystem; Influenza A, organism-specific biosystem; Influenza A, conserved biosystem; Measles, organism-specific biosystem
• Function: ATP binding; eukaryotic translation initiation factor 2alpha kinase activity; heme binding; nucleotide binding; protein homodimerization activity