Recombinant Mouse Eif2ak1 Protein, His-tagged

• Cat.No.: Eif2ak1-1411M
• Product Overview: Recombinant Mouse Eif2ak1 Protein (Phe167-Phe580) with N-His tag was expressed in E. coli.

Specification

• Description: Enables heme binding activity; protein homodimerization activity; and protein kinase activity. Involved in negative regulation of cell population proliferation and negative regulation of hemoglobin biosynthetic process. Acts upstream of or within several processes, including macrophage differentiation; protoporphyrinogen IX metabolic process; and regulation of cellular macromolecule biosynthetic process. Located in cytoplasm. Is expressed in alimentary system; central nervous system; liver; nervous system; and spinal cord. Orthologous to human EIF2AK1 (eukaryotic translation initiation factor 2 alpha kinase 1).
• Source: E. coli
• Species: Mouse
• Tag: His
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 50.2 kDa
  Accurate Molecular Mass: 50 kDa
• Protein length: Phe167-Phe580
• Purity: > 90%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Storage Buffer: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
• Reconstitution: Reconstitute in PBS or others.

Gene Information

• Gene Name: Eif2ak1 eukaryotic translation initiation factor 2 alpha kinase 1 [ Mus musculus (house mouse) ]
• Official Symbol: Eif2ak1
• Synonyms: EIF2AK1; eukaryotic translation initiation factor 2 alpha kinase 1; eukaryotic translation initiation factor 2-alpha kinase 1; heme-regulated inhibitor; heme-controlled repressor; hemin-sensitive initiation factor 2-alpha kinase; heme-regulated eukaryotic initiation factor eIF-2-alpha kinase; HCR; Hri; MGC118066
• Gene ID: 15467
• mRNA Refseq: NM_013557
• Protein Refseq: NP_038585
• UniProt ID: Q9Z2R9