Recombinant Human EGR2, GST-tagged

• Cat.No.: EGR2-12329H
• Product Overview: Recombinant Human EGR2 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Description: The protein encoded by this gene is a transcription factor with three tandem C2H2-type zinc fingers. Defects in this gene are associated with Charcot-Marie-Tooth disease type 1D (CMT1D), Charcot-Marie-Tooth disease type 4E (CMT4E), and with Dejerine-Sottas syndrome (DSS). Multiple transcript variants encoding two different isoforms have been found for this gene.
• Source: E.coli
• Species: Human
• Tag: GST
• Protein length: 149-499a.a.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: EGR2 early growth response 2 [ Homo sapiens ]
• Official Symbol: EGR2
• Synonyms: EGR2; early growth response 2; early growth response 2 (Krox 20 homolog, Drosophila) , KROX20; E3 SUMO-protein ligase EGR2; Krox 20 homolog; Drosophila; zinc finger protein Krox-20; early growth response protein 2; KROX-20, Drosophila, homolog (early growth response-2); AT591; CMT1D; CMT4E; KROX20; FLJ14547; DKFZp686J1957
• Gene ID: 1959
• mRNA Refseq: NM_000399
• Protein Refseq: NP_000390
• MIM: 129010
• UniProt ID: P11161
• Chromosome Location: 10q21.1
• Pathway: Adipogenesis, organism-specific biosystem; Calcineurin-regulated NFAT-dependent transcription in lymphocytes, organism-specific biosystem; Developmental Biology, organism-specific biosystem; HTLV-I infection, organism-specific biosystem; HTLV-I infection, conserved biosystem; IL4-mediated signaling events, organism-specific biosystem; Transcriptional Regulation of White Adipocyte Differentiation, organism-specific biosystem
• Function: DNA binding; RNA polymerase II activating transcription factor binding; chromatin binding; ligase activity; metal ion binding; protein binding; sequence-specific DNA binding transcription factor activity; transcription regulatory region DNA binding; ubiqu