Recombinant Human EGFR Protein, ECD, Tag Free, Biotinylated

• Cat.No.: EGFR-073H
• Product Overview: Recombinant human EGFR (erbb1) protein was developed from CHO cells.

Specification

• Species: Human
• Source: CHO
• Tag: Non
• Protein Length: ECD
• Description: The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor, thus inducing receptor dimerization and tyrosine autophosphorylation leading to cell proliferation. Mutations in this gene are associated with lung cancer. EGFR is a component of the cytokine storm which contributes to a severe form of Coronavirus Disease 2019 (COVID-19) resulting from infection with severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2).
• Conjugation/Label: Biotin
• Form: Lyophilised
• Endotoxin: Endotoxin level was found to be less than 0.1 ng/μg (1 EU/μg).
• Applications: ELISA, WB
• Notes: FOR RESEARCH USE ONLY (RUO).
• Storage: Recombinant EGFR can be stored in working aliquots at 2 to 8 centigrade for one month, or at -20 to -70 centigrade for 1 year. It is recommended to add 0.1% HSA or BSA for long term storage. Avoid repeated freeze/thaw cycles.
• Storage Buffer: Lyophilised from 0.2 μm filtered PBS pH 7.4 with 10% trehalose.
• Reconstitution: Upon receipt a quick spin of the vial followed by reconstitution in sterile PBS pH 7.4 to a concentration not less than 0.1 mg/mL. Solubilize for 1hr at room temp with gentle mixing.

Gene Information

• Gene Name: EGFR epidermal growth factor receptor [ Homo sapiens (human) ]
• Official Symbol: EGFR
• Synonyms: EGFR; epidermal growth factor receptor; epidermal growth factor receptor (avian erythroblastic leukemia viral (v erb b) oncogene homolog), ERBB; ERBB1; erythroblastic leukemia viral (v erb b) oncogene homolog (avian); proto-oncogene c-ErbB-1; cell growth inhibiting protein 40; cell proliferation-inducing protein 61; receptor tyrosine-protein kinase erbB-1; avian erythroblastic leukemia viral (v-erb-b) oncogene homolog; ERBB; HER1; mENA; PIG61
• Gene ID: 1956
• mRNA Refseq: NM_005228
• Protein Refseq: NP_005219
• MIM: 131550
• UniProt ID: P00533