Recombinant Human EGFR protein, DDK/His-tagged

Cat.No. : EGFR-193H
Product Overview : Recombinant Human EGFR(Leu25 - Ser645) fused with DDK/His tag at C-terminal was expressed in HEK293.
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Description : The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer.
Source : HEK293
Species : Human
Tag : His&Flag
Form : 1 x PBS, pH7.4, 10% glycerol.
Molecular Mass : 71 kDa
Protein length : Leu25 - Ser645
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions.
Concentration : >50 ug/mL as determined by microplate BCA method
Gene Name EGFR epidermal growth factor receptor [ Homo sapiens ]
Official Symbol EGFR
Synonyms EGFR; epidermal growth factor receptor; epidermal growth factor receptor (avian erythroblastic leukemia viral (v erb b) oncogene homolog) , ERBB; ERBB1; erythroblastic leukemia viral (v erb b) oncogene homolog (avian); proto-oncogene c-ErbB-1; cell growth inhibiting protein 40; cell proliferation-inducing protein 61; receptor tyrosine-protein kinase erbB-1; avian erythroblastic leukemia viral (v-erb-b) oncogene homolog; ERBB; HER1; mENA; PIG61;
Gene ID 1956
mRNA Refseq NM_005228
Protein Refseq NP_005219
MIM 131550
UniProt ID P00533

Not For Human Consumption!

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