Recombinant Human EDN2, GST-tagged

• Cat.No.: EDN2-12283H
• Product Overview: Recombinant Human EDN2 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Description: This gene encodes a member of the endothelin protein family of secretory vasoconstrictive peptides. The preproprotein is processed to a short mature form which functions as a ligand for the endothelin receptors that initiate intracellular signaling events. This gene product is involved in a wide range of biological processes, such as hypertension and ovulation.
• Source: E.coli
• Species: Human
• Tag: GST
• Protein length: 21-178a.a.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: EDN2 endothelin 2 [ Homo sapiens ]
• Official Symbol: EDN2
• Synonyms: EDN2; endothelin 2; endothelin-2; ET2; ET-2; preproendothelin 2; preproendothelin-2; PPET2
• Gene ID: 1907
• mRNA Refseq: NM_001956
• Protein Refseq: NP_001947
• MIM: 131241
• UniProt ID: P20800
• Chromosome Location: 1p34
• Pathway: Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; Direct p53 effectors, organism-specific biosystem; Endothelins, organism-specific biosystem; G alpha (q) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; GPCR ligand binding, organism-specific biosystem; Peptide ligand-binding receptors, organism-specific biosystem
• Function: endothelin B receptor binding; hormone activity