Recombinant Human EDF1, His-tagged
Cat.No. : | EDF1-28461TH |
Product Overview : | Recombinant full length protein, corresponding to amino acids 1-148 of Human EDF1 with N terminal His tag, 25kDa. |
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Description : | This gene encodes a protein that may regulate endothelial cell differentiation. It has been postulated that the protein functions as a bridging molecule that interconnects regulatory proteins and the basal transcriptional machinery, thereby modulating the transcription of genes involved in endothelial differentiation. This protein has also been found to act as a transcriptional coactivator by interconnecting the general transcription factor TATA element-binding protein (TBP) and gene-specific activators. Two alternatively spliced transcripts which encode distinct proteins have been found for this gene. |
Conjugation : | HIS |
Source : | E. coli |
Tissue specificity : | Expressed in brain, liver, lung, kidney and heart (at protein level). Ubiquitously expressed. More abundant in heart, pancreas, liver, intestine and adipose tissues. |
Form : | Lyophilised:Reconstitute with 48 μl aqua dest. |
Storage buffer : | Preservative: NoneConstituents: 0.5% Trehalose, 6M Urea, 100mM Sodium phosphate, 10mM Sodium chloride, pH 4.5 |
Storage : | Store at 4°C. Upon reconstitution store at -80oC. |
Sequences of amino acids : | MAESDWDTVTVLRKKGPTAAQAKSKQAILAAQRRGEDVET SKKWAAGQNKQHSITKNTAKLDRETEELHHDRVTLEVG KVIQQGRQSKGLTQKDLATKINEKPQVIADYESGRAIPNN QVLGKIERAIGLKLRGKDIGKPIEKGPRAK |
Sequence Similarities : | Contains 1 HTH cro/C1-type DNA-binding domain. |
Protein length : | 1-148 a.a. |
Full Length : | Full L. |
Gene Name | EDF1 endothelial differentiation-related factor 1 [ Homo sapiens ] |
Official Symbol | EDF1 |
Synonyms | EDF1; endothelial differentiation-related factor 1; EDF 1; multiprotein bridging factor 1; |
Gene ID | 8721 |
mRNA Refseq | NM_003792 |
Protein Refseq | NP_003783 |
MIM | 605107 |
Uniprot ID | O60869 |
Chromosome Location | 9q34.3 |
Function | calmodulin binding; NOT histone acetyltransferase activity; NOT methyltransferase activity; protein binding; sequence-specific DNA binding; |
Not For Human Consumption!
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