Recombinant Human Ectodysplasin A Receptor

• Cat.No.: EDAR-1607H

Specification

• Species: Human
• Source: Mammalian Cells
• Tag: Non
• Description: Ectodysplasin A receptor, also known as EDAR is a cell surface receptor of the tumor necrosis factor receptor (TNFR) family involved in the development of hair follicles, teeth, and sweat glands. EDAR is the genetic determinant of hair thickness as well as a strong contributor to hair fiber thickness variation among Asian populations.
• Molecular Weight: The predicted molecular weight of Recombinant Human EDAR is 44.3 kDa. However, the actual molecular weight as observed by migration on SDS Page is 55-60 kDa.
• State Of Matter: Lyophilized.
• Formulation: This recombinant protein was 0.2 µm filtered and lyophilized from modified Dulbecco's phosphate buffered saline (1X PBS) pH 7.2 – 7.3 with no calcium, magnesium, or preservatives.
• Purity: >90% by SDS Page and analyzed by silver stain.
• Endotoxin: <1.0 EU/µg as determined by the LAL method.
• Storage: This lyophilized protein is stable for six to twelve months when stored desiccated at -20℃ to -70℃. After aseptic reconstitution, this protein may be stored at 2℃ to 8℃ for one month or at -20℃ to -70℃ in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.

Gene Information

• Gene Name: EDAR ectodysplasin A receptor [ Homo sapiens ]
• Synonyms: EDAR; ectodysplasin A receptor; DL; ED3; ED5; ED1R; EDA3; HRM1; EDA1R; EDA-A1R; FLJ94390; ectodysplasin 1; anhidrotic receptor; Tumor necrosis factor receptor superfamily member EDAR; Anhidrotic ectodysplasin receptor 1; Ectodysplasin-A receptor; EDA-A1 receptor; Ectodermal dysplasia receptor; Downless homolog
• Gene ID: 10913
• mRNA Refseq: NM_022336
• Protein Refseq: NP_071731
• MIM: 604095
• UniProt ID: Q9UNE0
• Chromosome Location: 2q13
• Pathway: Cytokine-cytokine receptor interaction
• Function: protein binding; tumor necrosis factor receptor activity