Recombinant Human ECH1, GST-tagged
Cat.No. : | ECH1-12267H |
Product Overview : | Recombinant Human ECH1 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose. |
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Species : | Human |
Source : | E.coli |
Tag : | GST |
Protein Length : | 1-328a.a. |
Description : | This gene encodes a member of the hydratase/isomerase superfamily. The gene product shows high sequence similarity to enoyl-coenzyme A (CoA) hydratases of several species, particularly within a conserved domain characteristic of these proteins. The encoded protein, which contains a C-terminal peroxisomal targeting sequence, localizes to the peroxisome. The rat ortholog, which localizes to the matrix of both the peroxisome and mitochondria, can isomerize 3-trans,5-cis-dienoyl-CoA to 2-trans,4-trans-dienoyl-CoA, indicating that it is a delta3,5-delta2,4-dienoyl-CoA isomerase. This enzyme functions in the auxiliary step of the fatty acid beta-oxidation pathway. Expression of the rat gene is induced by peroxisome proliferators. |
Storage : | The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles. |
Storage Buffer : | 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol. |
Gene Name | ECH1 enoyl CoA hydratase 1, peroxisomal [ Homo sapiens ] |
Official Symbol | ECH1 |
Synonyms | ECH1; enoyl CoA hydratase 1, peroxisomal; enoyl Coenzyme A hydratase 1, peroxisomal; delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial; HPXEL; dienoyl-CoA isomerase; peroxisomal enoyl-CoA hydratase 1; delta3,5-delta2,4-dienoyl-CoA isomerase; |
Gene ID | 1891 |
mRNA Refseq | NM_001398 |
Protein Refseq | NP_001389 |
MIM | 600696 |
UniProt ID | Q13011 |
Chromosome Location | 19q13.1 |
Pathway | Fatty Acid Biosynthesis, organism-specific biosystem; Peroxisome, organism-specific biosystem; Peroxisome, conserved biosystem; |
Function | isomerase activity; protein binding; |
◆ Recombinant Proteins | ||
ECH1-12267H | Recombinant Human ECH1, GST-tagged | +Inquiry |
ECH1-1658R | Recombinant Rat ECH1 Protein, His (Fc)-Avi-tagged | +Inquiry |
ECH1-2812H | Recombinant Human Enoyl CoA Hydratase 1, Peroxisomal, His-tagged | +Inquiry |
ECH1-4965M | Recombinant Mouse ECH1 Protein | +Inquiry |
ECH1-486H | Recombinant Human ECH1, His tagged | +Inquiry |
◆ Cell & Tissue Lysates | ||
ECH1-6730HCL | Recombinant Human ECH1 293 Cell Lysate | +Inquiry |
Not For Human Consumption!
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