Recombinant Human EARS2, GST-tagged

• Cat.No.: EARS2-12255H
• Product Overview: Recombinant Human EARS2 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Species: Human
• Source: E.coli
• Tag: GST
• Protein Length: C-term-351a.a.
• Description: Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. The protein encoded by this gene belongs to the class-I aminoacyl-tRNA synthetase family and catalyzes the attachment of glutamate to tRNA(Glu). Alternative splicing results in multiple transcript variants.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: EARS2 glutamyl-tRNA synthetase 2, mitochondrial (putative) [ Homo sapiens ]
• Official Symbol: EARS2
• Synonyms: EARS2; glutamyl-tRNA synthetase 2, mitochondrial (putative); probable glutamate--tRNA ligase, mitochondrial; glutamate tRNA ligase 2; mitochondrial (putative); KIAA1970; MSE1; gluRS; glutamate--tRNA ligase; glutamate tRNA ligase 2, mitochondrial; probable glutamyl-tRNA synthetase, mitochondrial
• Gene ID: 124454
• mRNA Refseq: NM_001083614
• Protein Refseq: NP_001077083
• MIM: 612799
• UniProt ID: Q5JPH6
• Chromosome Location: 16p12.3
• Pathway: Aminoacyl-tRNA biosynthesis, organism-specific biosystem; Aminoacyl-tRNA biosynthesis, conserved biosystem; Aminoacyl-tRNA biosynthesis, eukaryotes, organism-specific biosystem; Aminoacyl-tRNA biosynthesis, eukaryotes, conserved biosystem; Gene Expression, organism-specific biosystem; Metabolic pathways, organism-specific biosystem; Mitochondrial tRNA aminoacylation, organism-specific biosystem
• Function: ATP binding; RNA binding; glutamate-tRNA ligase activity; glutamate-tRNA(Gln) ligase activity; ligase activity; nucleotide binding