Recombinant Human E4F1 cell lysate

• Cat.No.: E4F1-522HCL

Specification

• Species: Human
• Tag: Non
• Description: The zinc finger protein encoded by this gene is one of several cellular transcription factors whose DNA-binding activities are regulated through the action of adenovirus E1A. A 50-kDa amino-terminal product is generated from the full-length protein through proteolytic cleavage. The protein is differentially regulated by E1A-induced phosphorylation. The full-length gene product represses transcription from the E4 promoter in the absence of E1A, while the 50-kDa form acts as a transcriptional activator in its presence.
• Size: 100 ul
• Storage Buffer: 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
• Applications: Western Blot

Gene Information

• Gene Name: E4F1 E4F transcription factor 1 [ Homo sapiens ]
• Official Symbol: E4F1
• Synonyms: E4F1; E4F transcription factor 1; transcription factor E4F1; E4F; p50E4F; p120E4F; transcription factor E4F; putative E3 ubiquitin-protein ligase E4F1; MGC99614
• Gene ID: 1877
• mRNA Refseq: NM_004424
• Protein Refseq: NP_004415
• MIM: 603022
• UniProt ID: Q66K89
• Chromosome Location: 16p13.3
• Pathway: p53 pathway, organism-specific biosystem
• Function: DNA binding; cAMP response element binding; ligase activity; metal ion binding; protein binding; sequence-specific DNA binding transcription factor activity; transcription coactivator activity; transcription corepressor activity; zinc ion binding