Recombinant Human DYX1C1, His-tagged

Cat.No. : DYX1C1-12242H
Product Overview : Recombinant Human DYX1C1 protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.
Availability March 14, 2025
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Species : Human
Source : E.coli
Tag : His
Protein Length : 1-381a.a.
Description : This gene encodes a tetratricopeptide repeat domain-containing protein. The encoded protein interacts with estrogen receptors and the heat shock proteins, Hsp70 and Hsp90. An homologous protein in rat has been shown to function in neuronal migration in the developing neocortex. A chromosomal translocation involving this gene is associated with a susceptibility to developmental dyslexia. Mutations in this gene are associated with deficits in reading and spelling. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the downstream cell cycle progression 1 (CCPG1) gene.
Storage : The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
Storage Buffer : 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.
Gene Name DYX1C1 dyslexia susceptibility 1 candidate 1 [ Homo sapiens ]
Official Symbol DYX1C1
Synonyms DYX1C1; dyslexia susceptibility 1 candidate 1; dyslexia susceptibility 1 candidate gene 1 protein; EKN1; FLJ37882; RD; DYX1; DYXC1; MGC70618;
Gene ID 161582
mRNA Refseq NM_001033559
Protein Refseq NP_001028731
MIM 608706
UniProt ID Q8WXU2
Chromosome Location 15q21.1
Function estrogen receptor binding; protein binding;

Not For Human Consumption!

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