Recombinant Full Length Human DYX1C1 Protein, GST-tagged

• Cat.No.: DYX1C1-4095HF
• Product Overview: Human DYX1C1 full-length ORF ( AAH62564.1, 1 a.a. - 381 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes a tetratricopeptide repeat domain-containing protein. The encoded protein interacts with estrogen receptors and the heat shock proteins, Hsp70 and Hsp90. An homologous protein in rat has been shown to function in neuronal migration in the developing neocortex. A chromosomal translocation involving this gene is associated with a susceptibility to developmental dyslexia. Mutations in this gene are associated with deficits in reading and spelling. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the downstream cell cycle progression 1 (CCPG1) gene. [provided by RefSeq, Mar 2011]
• Source: In Vitro Cell Free System
• Species: Human
• Tag: GST
• Molecular Mass: 70.6 kDa
• Protein length: 381 amino acids
• AA Sequence: MPLQVSDYSWQQTKTAVFLSLPLKGVCVRDTDVFCTENYLKVNFPPFLFEAFLYAPIDDESSKAKIGNDTIVFTLYKKEAAMWETLSVTGVDKEMMQRIREKSILQAQERAKEATEAKAAAKREDQKYALSVMMKIEEEERKKIEDMKENERIKATKALEAWKEYQRKAEEQKKIQREEKLCQKEKQIKEGRKKIKYKSLTRNLASRNLAPKGRNSENIFTEKLKEDSIPAPRSVGSIKINFTPRVFPTALRESQVAEEEEWLHKQAEARRAMNTDIAELCDLKEEEKNPEWLKDKGNKLFATENYLAAINAYNLAIRLNNKMPLLYLNRAVCHLKLKNLHKAIEDSSKEFCSLEGIECQASEPKLSHHIPSDLHVYIQMA
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: DYX1C1 dyslexia susceptibility 1 candidate 1 [ Homo sapiens ]
• Official Symbol: DYX1C1
• Synonyms: DYX1C1; dyslexia susceptibility 1 candidate 1; dyslexia susceptibility 1 candidate gene 1 protein; EKN1; FLJ37882; RD; DYX1; DYXC1; MGC70618
• Gene ID: 161582
• mRNA Refseq: NM_001033559
• Protein Refseq: NP_001028731
• MIM: 608706
• UniProt ID: Q8WXU2