Recombinant Human DYRK1B, GST-tagged

• Cat.No.: DYRK1B-12237H
• Product Overview: Recombinant Human DYRK1B protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Description: DYRK1B is a member of the DYRK family of protein kinases. DYRK1B contains a bipartite nuclear localization signal and is found mainly in muscle and testis. The protein is proposed to be involved in the regulation of nuclear functions. Three isoforms of DYRK1B have been identified differing in the presence of two alternatively spliced exons within the catalytic domain.
• Source: E.coli
• Species: Human
• Tag: GST
• Protein length: 111-431a.a.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: DYRK1B dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B [ Homo sapiens ]
• Official Symbol: DYRK1B
• Synonyms: DYRK1B; dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B; dual specificity tyrosine-phosphorylation-regulated kinase 1B; minibrain related kinase; MIRK; mirk protein kinase; minibrain-related kinase
• Gene ID: 9149
• mRNA Refseq: NM_004714
• Protein Refseq: NP_004705
• MIM: 604556
• UniProt ID: Q9Y463
• Chromosome Location: 19q12-q13.1
• Function: ATP binding; nucleotide binding; protein binding; protein kinase activity; protein serine/threonine kinase activity; protein serine/threonine/tyrosine kinase activity; protein tyrosine kinase activity; transcription coactivator activity