Recombinant Human DYRK1B Protein, GST-tagged

• Cat.No.: DYRK1B-22H
• Product Overview: Recombinant full-length human DYRK1B was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.

Specification

• Description: This gene encodes a member of a family of nuclear-localized protein kinases. The encoded protein participates in the regulation of the cell cycle. Expression of this gene may be altered in tumor cells, and mutations in this gene were found to cause abdominal obesity-metabolic syndrome 3. Alternative splicing results in multiple transcript variants.
• Source: Insect cells
• Species: Human
• Tag: GST
• Molecular Mass: 106 kDa
• Purity: >90%
• Stability: One year at -70 centigrade from the date of shipment.
• Storage: Store product at –70 centigrade. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
• Concentration: 0.5 μg/μL
• Storage Buffer: 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol.

Gene Information

• Gene Name: DYRK1B dual specificity tyrosine phosphorylation regulated kinase 1B [ Homo sapiens (human) ]
• Official Symbol: DYRK1B
• Synonyms: DYRK1B; dual specificity tyrosine phosphorylation regulated kinase 1B; MIRK; AOMS3; dual specificity tyrosine-phosphorylation-regulated kinase 1B; dual specificity tyrosine-(Y)-phosphorylation regulated kinase 1B; minibrain-related kinase; mirk protein kinase; EC 2.7.12.1
• Gene ID: 9149
• mRNA Refseq: NM_004714
• Protein Refseq: NP_004705
• MIM: 604556
• UniProt ID: Q9Y463